Simparica Trio is a veterinarian-prescribed medication designed to protect dogs from a range of parasites. This chewable tablet offers comprehensive defense against fleas, ticks, heartworms, and intestinal worms. Containing three active ingredients – sarolaner, moxidectin, and pyrantel – Simparica Trio simplifies parasite prevention by addressing multiple threats in a single monthly dose.
It’s crucial to note that Simparica Trio is not available over-the-counter. A veterinarian’s prescription is required to ensure it’s the right choice for your dog.
Sarolaner, one of the key components, acts as both an insecticide and acaricide. It disrupts the nervous system of fleas and ticks, leading to their paralysis and death. This ingredient is effective against various tick species, including Gulf Coast ticks, brown dog ticks, deer ticks (black-legged ticks), American dog ticks, and Lone Star ticks.
Moxidectin, another active ingredient, is a parasiticide specifically targeting heartworm larvae, preventing heartworm disease. Pyrantel, the third component, is a nematocide that combats intestinal worms like hookworms and roundworms.
Key Advantages of Simparica Trio
Simparica Trio offers several significant benefits for dog owners:
- Broad-Spectrum Protection: It safeguards dogs against heartworm disease, fleas, ticks, roundworms, and hookworms, simplifying parasite prevention.
- Convenient Monthly Dose: The chewable tablet is administered just once a month, making it easy to incorporate into your dog’s routine.
- Safe for Young Puppies: Simparica Trio is safe for puppies as young as eight weeks old, weighing at least 2.8 pounds.
How to Administer Simparica Trio
Simparica Trio is given orally as a chewable tablet, typically once a month.
For heartworm prevention, it should be administered monthly, ideally starting within a month of mosquito exposure. If a dose is missed, administer it as soon as possible.
To prevent flea infestations, monthly administration is recommended, especially starting one month before flea season begins. Treating all dogs in a household is essential to prevent re-infestation.
Monthly treatments are also necessary for tick and intestinal nematode infestations.
Is Simparica Trio Right for Your Dog?
Simparica Trio is generally safe for dogs aged eight weeks and older, weighing at least 2.8 pounds. However, it’s not recommended for pregnant or lactating dogs. Crucially, dogs should be tested for existing heartworm disease before starting Simparica Trio, as it does not kill adult heartworms and could potentially worsen the condition if adult heartworms are already present.
Simparica Trio Dosage Guide
Simparica Trio is administered orally once a month, with the dosage based on your dog’s weight.
The recommended minimum dosage is 0.54mg/lb (1.19 mg/kg) sarolaner, 0.11mg/lb (0.24 mg/kg) moxidectin, and 2.27mg/lb (5.00 mg/kg) pyrantel.
| Body weight | Sarolaner per Tablet (mg) | Moxidectin per tablet (mg) | Pyrantel per tablet (mg) | Number of Tablets |
|---|---|---|---|---|
| 2.8 – 5.5 lbs (1.25 – 2.5 kg) | 3 | 0.06 | 12.5 | one |
| 5.6 – 11 lbs (2.5 – 5 kg) | 6 | 0.12 | 25 | one |
| 11.1 – 22 lbs (5 – 10 kg) | 12 | 0.24 | 50 | one |
| 22.1 – 44 lbs (10 – 20 kg) | 24 | 0.48 | 100 | one |
| 44.1 – 88 lbs (20 – 40 kg) | 48 | 0.96 | 200 | one |
| 88.1 – 132 lbs (40 – 60 kg) | 72 | 1.44 | 300 | one |
Supervise your dog after administration to ensure the entire tablet is swallowed and not discarded. If a dose is missed, give Simparica Trio immediately.
Potential Side Effects
Side effects from Simparica Trio are uncommon. Clinical trials have reported vomiting and diarrhea as potential adverse reactions. Other less frequent side effects may include lethargy, hyperactivity, reduced appetite, and increased urination.
Important Precautions
- Keep Simparica Trio tablets in their original packaging to prevent accidental ingestion by children.
- Wash hands thoroughly after administering the medication.
- If accidental ingestion occurs, seek medical advice immediately.
Simparica Trio Effectiveness
Studies have demonstrated Simparica Trio’s effectiveness in preventing and treating heartworm, fleas, and ticks. It is a reliable option for controlling these parasites in adult dogs and puppies.
Product Availability
Simparica Trio chewable tablets (containing sarolaner, moxidectin, and pyrantel) are available in six different tablet strengths, packaged in boxes of three or six tablets.
